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Not All Sugar Acts the Same
Glucose is tightly regulated and readily used as immediate fuel.
Fructose is metabolized differently, initiating a pathway that influences how cells allocate energy. When activated frequently, this pathway may shift how the body prioritizes storage and conservation. [1, 2].
SugarShield is formulated with research-studied ingredients to support healthy regulation of this pathway within normal metabolic function, focusing on a single clearly defined target.[3, 4].
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SugarShield: Precision Fructose Support
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SugarShield is a fructose-focused nutritional formula featuring research-studied luteolin and tart cherry extract, selected for their roles in supporting healthy fructose metabolism and normal cellular energy regulation.
Each bottle provides 60 servings (typically a one-month supply) and uses a liposomal delivery system designed to support ingredient absorption.
Designed for those seeking a more focused approach to metabolic support in a world of constant sugar exposure.
* SugarShield is based on publicly available research on luteolin, tart cherry, and fructose metabolism, and is formulated independently with no affiliation to any university or research institution. These statements have not been evaluated by the Food and Drug Administration. SugarShield is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease.
Research Context Behind the Formula
Supports normal fructose metabolism as part of overall metabolic health.
Luteolin is a plant-derived compound studied for its involvement in normal metabolic pathways. Early research suggests it may interact with enzymes related to fructose metabolism, including fructokinase (KHK). In human studies of luteolin-rich formulations, researchers observed changes in metabolic markers associated with dietary fructose intake.¹²³⁴
- 43% Insulin Resistance In a 6-month randomized trial in adults with metabolic dysfunction, luteolin-rich formulations were associated with a 43% reduction in HOMA-IR.
- 22% Liver Fat In the same 6-month randomized trial, luteolin-rich formulations were associated with a 22% reduction in markers of liver fat.
Why this matters for SugarShield
Luteolin has been studied for its interaction with metabolic pathways involved in fructose handling and cellular energy regulation.
SugarShield features a high-purity liposomal form of luteolin paired with tart cherry extract, selected to support normal metabolic function and cellular energy.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Footnotes:
1. Ducloux D., Clin J Am Soc Nephrol, 2024; 19(6): 807–809. doi: 10.2215/CJN.0000000000000442
2. Castellino G, Nikolic D, Magán-Fernández A, et al. Nutrients. 2019;11(11):2580. doi:10.3390/nu11112580
3. Nikolic D, Bjelakovic B, Castellino G, et al. Nutrients. 2023;15(2), 462. doi:10.3390/nu15020462
4. Pfizer PF-06835919 Phase 2 Trial: Clinical Study C1061011 (NCT03202760). Plain Language Summary. Pfizer, 2023.
Guided By The Research
A clear explanation of the fructose pathway, why it matters, and how we think about metabolic resilience.
Formulated with Research-Studied Ingredients
Each ingredient is selected for its role in metabolic pathways linked to fructose handling and cellular energy.
Rooted in Research. Built on Trust.
Every detail behind SugarShield — from formulation to philosophy — reflects a deep commitment to evidence-based metabolic care.
Dr. Paul Gross
A practicing physician for over 15 years, Dr. Gross provides clinical oversight for SugarShield. With a focus on metabolic dysfunction and preventative care, he ensures the formulation is both grounded in research and safe for real-world use.
Chris Mearns
Founder of LIV3, Chris has spent years investigating how fructose metabolism drives metabolic dysfunction — a scientific paradigm shift now gaining traction across research circles, biohacking communities, and podcasts like Boost Your Biology.
Scientific Advances for Metabolic Efficiency
A 2024 scientific review called luteolin “a promising multifunctional natural flavonoid for human diseases,” citing benefits across metabolic, vascular, neurological, and even oncological systems — suggesting broad support for overall physiological balance.
Luteolin was the top-ranked compound for boosting cellular energy in a screen of 1,200 FDA-approved molecules.
In a 6-month human trial, a luteolin-rich nutraceutical significantly reduced body weight and improved body composition.
Luteolin increases leptin production in fat cells and restores satiety signaling — a dual reset for hunger control.
Luteolin blocks sugar’s toxic conversion into uric acid — while tart cherry extract supports its natural clearance.
In a 6-month human trial, a luteolin-rich nutraceutical improved liver fat, insulin resistance, cholesterol, and inflammation.
Luteolin improves insulin signaling from the cell membrane to the nucleus — with human trials confirming reduced insulin resistance.
Luteolin inhibits key inflammatory pathways at the cellular level — with evidence of relief in arthritis, joint degeneration, and inflammatory overload.
Luteolin supports hormonal balance by improving insulin sensitivity, reducing oxidative stress, and normalizing reproductive hormone levels in PCOS models.
Luteolin outperformed cromolyn — a prescription mast cell blocker — in reducing histamine and cytokine release, offering a promising strategy for MCAS, neuroinflammation, and allergic responses.
Luteolin calms neuroinflammation and recharges low-energy neurons — targeting the root of brain fog, low mood, memory loss, and degeneration.
Validated with DEXAfit Imaging
In collaboration with DEXAfit, we conduct ongoing body composition validation in select LIV3 customers. Using clinical-grade DEXA imaging, we track changes in total fat mass, lean mass, and visceral fat over time.
This allows us to observe how modulating fructose metabolism may influence tissue-level health markers beyond the scale.
From time to time, SugarShield customers are invited to participate. Selected participants may receive complimentary DEXA scans and product support during the study period.
Participation is invitation-only and limited to active SugarShield customers.
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What People Feel First
600K+ meals shielded ★ 4.9 ratingIt starts with energy — then cascades into focus, control, and balance.
“I'm shocked at how good my energy/mood has been on it. This is going to be my new staple.”
— Lucas Aoun, Boost Your Biology
“I’ve lost weight without even trying.”
— Tash
"I'm loving the massively reduced food noise/cravings!"
— Matty Lansdown, The Real Weight Loss Coach
“I can’t believe the difference I feel.”
— Luca
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