Cellular Energy
In a screen of 1,200 compounds, luteolin emerged as a leading candidate for increasing cellular energy. Follow-up experiments showed stronger mitochondrial activity in neurons.
Naia et al., BMC Biology (2021)
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Support for the sugar you can't avoid.
Feel like yourself again.
Our customers consistently describe steadier energy, fewer cravings, and less food noise. Behind the bottle: cutting-edge research into fructose and cellular energy.
$49.95$89.95SAVE 44%
One capsule with meals. 60 servings a bottle. Free shipping over $99.
98%
Luteolin purity
Liposomal
Delivery
60
Servings a bottle
2
Ingredients, no filler
Reviews
What people feel first.
It starts with energy, then cascades into focus, control, and balance.
Individual results vary. These are unedited customer reviews and are not a promise of any particular outcome. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
I'm shocked at how good my energy and mood has been on it. This is going to be my new staple.
I'm loving the massively reduced food noise and cravings.
I've lost weight without even trying.
Two ingredients, one enzyme, and a lot of reading.
Here is what stands behind the bottle.
How it works
Fructose tells your body to store.
More than a source of calories, fructose can signal your body to conserve energy and build fat reserves.
The signal
Conservation mode
Table sugar pairs fuel with a signal. Its glucose half supplies energy; its fructose half can signal your body to conserve energy and store fat.
How many times a day are you telling your body to store more?
With SugarShield
Turn down the signal
SugarShield contains luteolin, studied in laboratory research for inhibiting fructokinase, the enzyme that starts fructose metabolism. By targeting that first step, we aim to protect cellular energy and turn down the signal to conserve and store.
Nobody's coming for your apple. Fructose has made itself quite at home in modern life.
Sugar in disguise
Sugar has 60+ aliases and a very good agent.
Organic cane sugar. Coconut sugar. Raw honey. Agave nectar. They sound right at home in the health-food aisle. They still bring fructose with them. And your body can make its own, too.
Before the first meeting.Sweeten your latte with 20g of table sugar and 10g is fructose. The coffee didn't come alone.
Breakfast. Snack. Repeat.Sweetened yogurt. Granola clusters. That afternoon cereal bar. Added sugars can bring fructose into several stops in your day, without dessert ever entering the picture.
No sugar required.Fries. White bread. Another round. It doesn't have to taste sweet: research suggests excess salt, high blood glucose, and alcohol can prompt your body to make fructose of its own.
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Modern life keeps putting fructose on the menu. Even when you didn't order it.
What's inside
Formulas That Work. No BS, Just Better.
There are only two ingredients, luteolin for the enzyme and tart cherry for the uric acid that comes with it.
Get Started
sugar freeketovegandairy freegluten freesoy freesugar freeketovegandairy freegluten freesoy free
Liposomal Luteolin
Studied for how it interacts with fructokinase, the enzyme that starts fructose metabolism. Wrapped in a lipid layer because luteolin absorbs poorly on its own. Blocking that step is intended to help preserve cellular energy.
Tart Cherry
Included for its part in uric acid handling. Uric acid is the byproduct fructose leaves behind, and elevated uric acid is linked to oxidative stress and inflammation, so the two ingredients work the same problem from either end.
LiposomalDelivery
3rd-partyTested
98%Luteolin purity
cGMPManufactured
6-month randomised trial
43%Difference
Insulin Resistance
Measured as HOMA-IR, in adults with metabolic dysfunction.
Read the studyThe research
What the trial found.
Two numbers from a six-month randomised trial of a luteolin-rich formulation. That is research on the compound rather than on our bottle, and we would rather say so than blur it.
Same trial
27%Difference
Fatty Liver Index
Markers of hepatic fat across the same six months.
Read the studyFootnotes:
4. Pfizer PF-06835919 Phase 2 Trial: Clinical Study C1061011 (NCT03202760). Plain Language Summary. Pfizer, 2023.
Figures show differences in percentage changes favouring treatment over placebo after six months, rounded to the nearest percentage point. These findings describe research on luteolin-rich formulations and are given as scientific context, not as claims about SugarShield. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Try SugarShield for 90 days
Take one capsule with meals. Most people start with three jars, because a single month is not really long enough to tell.
Not feeling it? Email us.Get in touch inside 30 days and we will sort it out. No forms, no restocking fee.
Who is behind it
We publish the whole argument.
Reframing metabolism for millions. Chris's work is helping shape a growing shift in how metabolism, obesity, and chronic disease are understood. He spent years on a single question, then put the entire model online for free and asked people to try to break it. That invitation is still open, and so are the comments.
What the research covers
Luteolin turns up in a lot of different rooms.
Cellular energy. Metabolism. Inflammation. Brain health. Luteolin appears across a remarkably broad range of research, a scope explored in this 2024 review.
Below are ten findings, each with the study behind it. Human trials, animal studies and cell experiments are identified on each card. Tap any one to see what the researchers found.
Weight Control
A 50-person analysis of a six-month randomized trial found greater weight loss with an artichoke formulation containing luteolin and chlorogenic acid than with placebo.
Terzo et al., Nutrients (2023)
Blood Vessel Health
In rats with type 2 diabetes, luteolin improved blood vessel relaxation and reduced inflammation in the surrounding fat tissue.
Queiroz et al., International Journal of Molecular Sciences (2021)
Uric Acid
In a small four-week trial involving ten adults, a standardized tart cherry extract lowered blood uric acid compared with placebo.
Jäger et al., Journal of Dietary Supplements (2026)Metabolic Health
A 50-person analysis of a six-month randomized trial found that an artichoke formulation containing luteolin improved blood sugar, cholesterol and Fatty Liver Index, a score estimating fatty liver likelihood.
Terzo et al., Nutrients (2023)Insulin Sensitivity
The 50-person trial analysis described above also found improved insulin resistance, measured using fasting glucose and insulin, with the artichoke formulation compared with placebo.
Terzo et al., Nutrients (2023)Inflammation & Joints
In rats with experimentally induced osteoarthritis, oral luteolin improved pain-related behaviour and reduced an inflammatory marker in cartilage.
Wang et al., Front Pharmacol (2023)PCOS and Hormones
In a rat model of obesity and PCOS, luteolin improved glucose tolerance, reduced liver fat and restored more regular reproductive cycles.
Huang & Zhang, Am J Physiol Endocrinol Metab (2021)Histamine & Mast Cells
In cultured human mast cells, luteolin inhibited histamine release more strongly than cromolyn, a prescription mast cell stabilizer.
Tsilioni & Theoharides, Int Arch Allergy Immunol (2024)Brain Health
In aged mice, dietary luteolin improved spatial working memory and reduced inflammatory signalling in the hippocampus, a brain region central to memory.
Kempuraj et al., Biofactors (2021)Every line above describes published research on luteolin or tart cherry, provided as scientific context rather than as claims about SugarShield. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Validated with DEXAfit
We measure what the scale can't.
Clinical-grade DEXA imaging on selected customers, tracking real tissue change over time rather than a number that moves for a dozen reasons.
Participation is invitation-only and limited to active SugarShield customers. Selected participants may receive complimentary scans and product support for the study period.
Contact us for details
FAQs
Things people ask us.
How is SugarShield different?
SugarShield is built around research into fructose metabolism and cellular energy. It pairs luteolin, studied in laboratory research for inhibiting fructokinase, with tart cherry extract. Fructokinase starts the main pathway for breaking down fructose. Our aim is to support cellular energy by targeting that early step.
Is SugarShield relevant if I already limit sugar?
Limiting added sugar is a useful starting point. The body can also make fructose internally under certain conditions, so our interest in this pathway extends beyond the sugar you eat. That explains the approach, but it does not establish that everyone eating a low-sugar diet will benefit.
Do I need to avoid fruit?
No. Whole fruit provides fibre, water and valuable nutrients, and can remain part of a balanced diet. Our focus is excess sugar intake, especially from sweetened drinks and added sugars. You do not need SugarShield to make eating fruit acceptable.
Has SugarShield itself been clinically tested?
The finished SugarShield formula has not yet been tested in a completed clinical trial. Our approach draws on laboratory and animal research, alongside human studies of ingredients and other formulations. Those studies help explain the rationale, but their results cannot be assumed to apply to SugarShield. Our research section identifies the type of evidence behind each finding.
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