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Why do cravings, weight gain, fatigue, fatty liver disease, insulin resistance, cardiovascular disease, hormonal dysfunction, and so many other conditions so often appear together?
Medicine studies these conditions separately because they affect different organs and systems. Yet in the real world, they frequently cluster in the same individuals, often progressing together over time.
Our conversation on The Real Weight Loss Coach explored one possible explanation.
Continue exploring the ideas, research, and practical tools discussed on the show.
We've assembled a collection of free resources for listeners who want to go deeper.
Inside you'll find:
Whether you agree with our conclusions or simply find the questions interesting, we hope these resources help you think more deeply about metabolism and health.
Download The Starter Kit STUB: replace href with real Starter Kit asset URLMost discussions about metabolism focus on fuel.
The Fructose Model explores an additional question:
What if metabolism is not only about fuel supply, but also about fuel allocation?
This short video provides a concise overview of the central idea explored throughout our work and serves as the best place to start if you're new to these concepts.
Sleep and metabolism run on the same circuit: how the body produces, stores, and recovers energy shapes both. Fructose metabolism is associated with insulin signaling, inflammation, and leptin patterns, all of which intersect with sleep quality and overnight recovery. Our work explores whether supporting that pathway consistently is a variable worth attention for people who treat sleep as a skill.
If you decide to explore these ideas, many people begin by paying attention to patterns that are often overlooked.
Common areas people track include:
The conversation on Sleep Is A Skill focused primarily on understanding the model.
SugarShield grew out of a simple follow-up question: if fructose metabolism plays an important role in metabolic health, what happens when that pathway is consistently supported over time?
Built directly in response to that research, SugarShield is a practical tool for people interested in applying these ideas in everyday life.
As a thank you for listening, we've included a special offer for the Sleep Is A Skill audience below.
Applied automatically at checkout.
SugarShield. $49.95. 60 servings per bottle. Precision Fructose Support.
Explore articles, videos, interviews, and educational content focused on metabolism, cellular energy, fructose biology, and emerging research.
Explore Education → ResearchReview scientific references, whitepapers, and deeper dives into the evidence that helped shape this framework.
Explore Research → Practical ApplicationsLearn how we think about supporting healthy fructose metabolism in everyday life and explore the tools developed around that perspective.
Explore SugarShield →The science of metabolism continues to evolve, and many of the questions that first captured our attention remain active areas of research today.
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LIV3 was founded by Chris Mearns after years of studying recurring patterns across obesity, insulin resistance, fatty liver disease, cardiovascular disease, and other chronic conditions. Dr. Paul Gross brings more than fifteen years of experience in metabolic health and preventive medicine, helping ensure that our interpretation of the science remains measured, evidence-based, and grounded in clinical reality.
We do not claim to have all the answers. We believe progress begins by asking better questions and following the evidence wherever it leads.
Dr. Paul Gross is a primary care physician with over 15 years of clinical practice and a Clinical Assistant Professor at the University of British Columbia. His work centers on metabolic dysfunction, insulin resistance, and chronic disease prevention, grounded in clinical research and community health.
At LIV3 Health, Dr. Gross provides clinical oversight for SugarShield, validating the formulation's scientific rigor, safety, and real-world efficacy. He played a key role in iterating the approach, ensuring it stays aligned with the latest advancements in metabolic health research.