What to Expect When Supplementing with Liposomal Luteolin and Tart Cherry Extract

The powerful ingredients in our products work together to support metabolic health by inhibiting fructokinase, an enzyme linked to fat storage and inflammation. However, the benefits of supplementation don’t appear overnight. Instead, they develop gradually as your body adjusts. Below, we’ve outlined a general timeline of potential effects to help you understand the stages of change you may experience and how consistent use can contribute to improved energy, reduced cravings, and better overall well-being. Keep in mind, individual results may vary based on your diet, lifestyle, and health.


When someone begins supplementing with at least 250mg of Liposomal Luteolin and 200mg Tart Cherry Extract twice daily — the two keystone compounds in our products — the gradual blocking of fructokinase will likely influence their metabolism in stages. Below is a hypothetical timeline outlining possible effects as their body adjusts to the new state:

Day 1: Initial Supplementation

• Physical Effects: Little to no immediate noticeable effects. The Luteolin and Tart Cherry Extract begin to enter the system and start to inhibit fructokinase slightly, though this will not yet lead to significant changes.
• Mental/Emotional Effects: Perhaps an initial placebo effect, where the individual feels they are taking positive steps towards better health.

Day 3: Beginning to Block fructokinase

• Physical Effects: As the Luteolin begins inhibiting fructokinase, some may start to feel slight changes in energy levels, particularly after meals containing fructose (e.g., sugary foods, HFCS). These energy fluctuations may be subtler, with less of a “sugar crash.”
• Cravings: Some reduction in sugar cravings may begin as the body starts to metabolize less fructose into fat and cellular stress is reduced.

Day 7: Initial Metabolic Shifts

• Energy: A more stable energy pattern may emerge. The reduced fructokinase activity may lower the body’s tendency to convert fructose into fat, possibly causing less of the highs and lows typically associated with high sugar intake.
• Mood: Improved mood or mental clarity may begin to emerge as inflammation caused by fructose metabolism decreases.
• Digestion: Some individuals may notice changes in digestion, as their body processes sugars more slowly. They might experience less bloating after meals that typically cause discomfort.

Day 14: Noticeable Shifts

• Energy and Fatigue: Individuals may start to notice more consistent energy throughout the day, with fewer crashes, especially after eating meals with some fructose. Fatigue related to high sugar intake may decrease.
• Weight: There may be subtle weight changes (e.g., less bloating), as fat storage from fructose is reduced. Weight loss, if any, will be modest, but some may experience a slight decrease in body fat or water retention.
• Inflammation: Decreased inflammation due to the antioxidant effects of Luteolin and Tart Cherry Extract might result in less joint pain, fewer headaches, or overall soreness.
• Sleep: Some users may notice slight improvements in sleep quality, as inflammation decreases and blood sugar regulation improves.

Day 30: Enhanced Benefits

• Weight and Body Composition: Small but potentially meaningful reductions in fat storage may become more noticeable, especially if the individual had high fructose intake before supplementation. The conversion of fructose into fat is further inhibited, so the individual may start to see changes in stubborn fat areas.
• Cravings and Appetite: Significant reduction in cravings for sweets may become apparent. The individual might find it easier to resist sugary foods and maintain a more balanced diet. There could be less desire for snacking, especially on sugary or high-carbohydrate foods.
• Mood and Cognitive Function: Reduced brain fog and more consistent mental clarity may emerge as the body has a more stable blood sugar response to meals.
• Inflammation and Pain: More pronounced reductions in inflammation may improve any pre-existing conditions linked to chronic inflammation (e.g., joint pain, mild headaches, or muscle soreness).

Day 60: Sustained Metabolic Adjustments

• Weight and Fat Loss: Individuals with higher initial fructose consumption may notice more apparent body composition changes by now. Weight loss might accelerate due to less fat being stored and possibly better energy metabolism.
• Energy Levels: Consistent, stable energy throughout the day with fewer crashes or spikes after meals will likely be noticeable. This steady state might result in higher productivity and improved motivation for physical activities.
• Mood and Cognitive Function: Further improvements in mood and cognitive clarity may be apparent. The person might experience enhanced mental focus and possibly an improved overall sense of well-being.
• Health Metrics: Blood tests (if conducted) may reveal improvements in markers of metabolic health, such as insulin sensitivity, blood glucose levels, and triglycerides.

Day 90 and Beyond: Long-Term Stabilization

• Weight and Fat Loss: If the individual continues on a healthy diet, weight loss and fat reduction might be sustainable over the long term. Those who had difficulty losing weight due to fructose-induced fat storage may now find it easier to maintain or continue losing weight.
• Cravings: Persistent sugar cravings should be significantly diminished, as the body has adapted to lower fructose intake and the subsequent impact on fat metabolism.
• Inflammation: Chronic inflammation, if previously an issue, might be considerably reduced. Conditions associated with inflammation (e.g., joint pain, skin conditions) may improve.
• Overall Health: This person might notice that they feel healthier and more resilient. They could also experience less post-meal drowsiness and improved post-exercise recovery times due to the anti-inflammatory effects of both supplements.

Long-Term Considerations

The long-term use of these supplements should contribute to a better overall metabolic profile. The reduction of fructose metabolism via fructokinase inhibition may prevent some of the long-term negative consequences of high fructose consumption, such as insulin resistance and fatty liver disease. Combined with a diet that limits processed sugars, these supplements could play a role in promoting a healthier lifestyle and mitigating the risks of metabolic syndrome.

These effects are hypothetical and may vary based on individual factors like baseline health, diet, lifestyle, and genetic predispositions.